{"id":2135,"date":"2013-09-27T20:34:24","date_gmt":"2013-09-27T17:34:24","guid":{"rendered":"http:\/\/www.tbeeb.net\/hma\/?p=2135"},"modified":"2021-10-12T08:44:43","modified_gmt":"2021-10-12T05:44:43","slug":"%d8%aa%d8%b4%d8%ae%d9%8a%d8%b5-%d8%b3%d8%b1%d8%b7%d8%a7%d9%86-%d8%a7%d9%84%d8%ab%d8%af%d9%8a-%d8%ac13","status":"publish","type":"post","link":"https:\/\/www.tbeeb.net\/health\/%d8%aa%d8%b4%d8%ae%d9%8a%d8%b5-%d8%b3%d8%b1%d8%b7%d8%a7%d9%86-%d8%a7%d9%84%d8%ab%d8%af%d9%8a-%d8%ac13\/","title":{"rendered":"\u062a\u0634\u062e\u064a\u0635 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a"},"content":{"rendered":"<p><!--more--><\/p>\n<p>\u0645\u0627 \u0632\u0644\u0646\u0627 \u0646\u0631\u0649 \u0627\u0644\u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0633\u064a\u062f\u0627\u062a \u064a\u0630\u0647\u0628\u0646 \u0628\u0623\u0646\u0641\u0633\u0647\u0646 \u0645\u0628\u0627\u0634\u0631\u0629 \u0625\u0644\u0649 \u0645\u0631\u0627\u0643\u0632 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\u0642\u062f \u0648\u0636\u0639\u062a \u0641\u064a \u0633\u0627\u0626\u0644 \u0641\u0648\u0631\u0645\u0627\u0644\u064a\u0646 \u0648\u0632\u0631\u0639\u0647\u0627 \u0648\u0641\u062d\u0635\u0647\u0627 \u0644\u062a\u062b\u0628\u064a\u062a \u0627\u0644\u062a\u0634\u062e\u064a\u0635 (Cell block) \u0648\u0631\u0628\u0645\u0627 \u0644\u0625\u062c\u0631\u0627\u0621 \u0641\u062d\u0635 \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0625\u0630\u0627 \u0623\u0645\u0643\u0646 \u0648\u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0648\u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0623\u0639\u062f\u0627\u062f\u0647\u0627 \u0643\u0627\u0641\u064a\u0629 \u0648\u062a\u0645 \u062d\u0641\u0638\u0647\u0627 \u062c\u064a\u062f\u0627\u064b \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u0645\u062c\u0647\u0632\u0627\u064b \u0644\u0630\u0644\u0643.<\/p>\n<h2>\u062b\u0627\u0646\u064a\u0627\u064b: \u062e\u0632\u0639\u0629 \u0628\u0627\u0644\u0625\u0628\u0631\u0629 \u0627\u0644\u0639\u0631\u064a\u0636\u0629 (Core Biopsy)<\/h2>\n<p>\u0647\u0630\u0647 \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u062a\u0633\u0645\u062d \u0644\u0644\u062c\u0631\u0627\u062d \u0623\u0648 \u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0645\u062a\u0645\u0631\u0646 \u0628\u0623\u0646 \u064a\u0633\u062d\u0628 \u062e\u0632\u0639\u0629 \u0633\u0645\u0627\u0643\u062a\u0647\u0627 \u0628\u0636\u0639\u0629 \u0645\u0644\u0645\u064a\u062a\u0631\u0627\u062a \u0648\u0637\u0648\u0644\u0647\u0627 \u0642\u062f \u064a\u0643\u0648\u0646 \u062d\u0648\u0627\u0644\u064a \u0627\u0644\u0633\u0646\u062a\u0645\u062a\u0631. \u0647\u0630\u0647 \u0627\u0644\u062e\u0632\u0639\u0629 \u062a\u0633\u0645\u062d \u0644\u0646\u0627 \u0628\u0641\u062d\u0635\u064d \u0623\u0641\u0636\u0644 \u0648\u0623\u0643\u062b\u0631 \u062f\u0642\u0629 \u0644\u0644\u0648\u0631\u0645 \u0648\u062a\u0641\u0631\u0642 \u062c\u064a\u062f\u0627 \u0628\u064a\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0623\u0648 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629. \u062a\u0633\u0645\u062d \u0647\u0630\u0647 \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0623\u064a\u0636\u0627\u064b \u0628\u0623\u0646 \u064a\u062a\u0645 \u0641\u062d\u0635 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0644\u0648\u062c\u0648\u062f \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0644\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0648\u0647\u064a\u06312 \u0646\u064a\u0648 (Estrogen and Progesteron Receptors and HER 2 neu) \u0641\u064a\u0647\u0627. \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0627\u0646 \u062a\u0633\u0627\u0644 \u0648\u0627\u0646 \u062a\u0633\u062a\u0639\u0644\u0645 \u0648\u0644\u0627 \u0628\u0623\u0633 \u0628\u0623\u0646 \u062a\u0639\u0631\u0641 \u0645\u0627 \u0647\u064a 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\u0645\u0627\u0630\u0627 \u064a\u0641\u0639\u0644 \u0627\u0644\u0637\u0628\u064a\u0628 \u0628\u0639\u062f \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0648\u0645\u0627 \u0647\u064a \u0627\u0644\u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0644\u062a\u064a \u064a\u062c\u0631\u0628\u0647\u0627 \u0627\u0644\u0637\u0628\u064a\u0628 \u0642\u0628\u0644 \u0627\u0644\u062c\u0631\u0627\u062d\u0629\u060c \u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0641\u062d\u0635 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u060c \u0641\u0647\u0646\u0627\u0643 \u062d\u062f \u0623\u062f\u0646\u0649 \u0645\u0646 \u0627\u0644\u0641\u062d\u0648\u0635\u0627\u062a \u064a\u062c\u0628 \u0625\u062c\u0631\u0627\u0624\u0647\u0627 \u0648\u0645\u0639\u0631\u0641\u0629 \u0646\u062a\u0627\u0626\u062c\u0647\u0627 \u0642\u0628\u0644 \u0627\u0644\u0628\u062f\u0621 \u0628\u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0648\u0630\u0644\u0643 \u0644\u0643\u064a \u062a\u0633\u0627\u0639\u062f 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\u064a\u0642\u0631\u0631 \u0627\u0644\u0637\u0628\u064a\u0628 \u0623\u0646 \u062a\u0643\u0648\u0646 \u062c\u0631\u0627\u062d\u0629 \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0628\u0646\u0641\u0633 \u0627\u0644\u0648\u0642\u062a \u062c\u0631\u0627\u062d\u0629 \u0639\u0644\u0627\u062c\u064a\u0629. \u064a\u0643\u0648\u0646 \u0639\u0644\u0649 \u0627\u0644\u0637\u0628\u064a\u0628 \u0647\u0646\u0627 \u0623\u0646 \u064a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0627\u0644\u0641\u062d\u0635 \u0627\u0644\u0646\u0633\u064a\u062d\u064a \u0627\u0644\u0645\u062b\u0644\u062c \u0648\u0627\u0644\u0641\u0648\u0631\u064a\u060c \u0648\u0623\u0646 \u064a\u0633\u062a\u0623\u0635\u0644 \u0627\u0644\u0648\u0631\u0645 \u0628\u0627\u0644\u0643\u0627\u0645\u0644 \u0648\u064a\u062a\u0623\u0643\u062f \u0645\u0646 \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u062e\u0644\u0627\u064a\u0627 \u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0639\u0644\u0649 \u062d\u062f\u0648\u062f 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\u0648\u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0629<\/h2>\n<p><strong>1 &#8211; \u0623\u0647\u0645\u064a\u0629 \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0646\u0633\u064a\u062c\u064a \u0642\u0628\u0644 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0629:<\/strong><\/p>\n<p>\u064a\u062c\u0628 \u0627\u0639\u062a\u0645\u0627\u062f \u0627\u0644\u0641\u062d\u0648\u0635\u0627\u062a \u0628\u0627\u0644\u0625\u0628\u0631\u0629 \u0627\u0644\u0631\u0641\u064a\u0639\u0629 \u0623\u0648 \u0627\u0644\u0639\u0631\u064a\u0636\u0629 \u0642\u0628\u0644 \u0625\u062c\u0631\u0627\u0621 \u0623\u064a\u0629 \u0639\u0645\u0644\u064a\u0629 \u062c\u0631\u0627\u062d\u064a\u0629.<\/p>\n<p><strong>2 &#8211; \u0625\u0646 \u0627\u0639\u062a\u0645\u0627\u062f \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0648\u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0641\u064a \u0648\u0642\u062a \u0648\u0627\u062d\u062f:<\/strong><\/p>\n<p>\u0647\u064a \u0637\u0631\u064a\u0642\u0629 \u0643\u0627\u0646\u062a \u0645\u062a\u0628\u0639\u0629 \u0641\u064a \u0627\u0644\u0633\u0627\u0628\u0642\u060c \u0648\u0625\u0646 \u0627\u0644\u0628\u0639\u0636 \u0645\u0646 \u0627\u0644\u0645\u0631\u0627\u0643\u0632 \u0648\u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0646 \u0645\u0627 \u0632\u0627\u0644\u0648\u0627 \u0644\u0644\u0623\u0633\u0641 \u064a\u0633\u062a\u0639\u0645\u0644\u0648\u0646\u0647\u0627\u060c \u0648\u0646\u062d\u0646 \u0644\u0627 \u0646\u0646\u0635\u062d \u0628\u0647\u0627 \u062d\u0627\u0644\u064a\u0627\u064b \u0627\u0644\u0627 \u0641\u064a \u0628\u0639\u0636 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062e\u0627\u0635\u0629 \u0627\u0644\u0636\u0631\u0648\u0631\u064a\u0629.<\/p>\n<p><strong>3 &#8211; \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0623\u0641\u0636\u0644: \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0623\u0648\u0644\u0627\u064b\u060c \u062b\u0645 \u0627\u0644\u062c\u0631\u0627\u062d\u0629 \u062b\u0627\u0646\u064a\u0627\u064b:<\/strong><\/p>\n<p>\u0625\u0646 \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u062b\u0645 \u0627\u0644\u062c\u0631\u0627\u062d\u0629 \u0639\u0644\u0649 \u0645\u0631\u062d\u0644\u062a\u064a\u0646 \u064a\u0633\u0645\u062d \u0628\u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u062f\u0642\u064a\u0642 \u0648\u0634\u0631\u062d \u062e\u064a\u0627\u0631\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u0644\u0645\u0631\u064a\u0636\u0629. \u0648\u0647\u064a \u0623\u064a\u0636\u0627\u064b \u0642\u062f \u062a\u0633\u0645\u062d \u0628\u062a\u0637\u0628\u064a\u0642 \u0637\u0631\u0642 \u062c\u062f\u064a\u062f\u0629 \u0644\u0644\u0639\u0644\u0627\u062c \u0645\u062b\u0644 \u0627\u0644\u062c\u0631\u0627\u062d\u0629 \u0627\u0644\u0645\u062d\u062f\u0648\u062f\u0629 \u0644\u0644\u0639\u0642\u062f \u0627\u0644\u0625\u0628\u0637\u064a\u0629 \u0627\u0644\u062d\u0627\u0631\u0633\u0629 \u0623\u0648 \u0625\u0639\u0637\u0627\u0621 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0642\u0628\u0644 \u0627\u0644\u062c\u0631\u0627\u062d\u0629.<\/p>\n<p><strong>4 &#8211; \u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0648\u0627\u0644\u062c\u0631\u0627\u062d\u0629 \u0628\u0648\u0642\u062a \u0648\u0627\u062d\u062f\u060c \u0625\u0630\u0627 \u0645\u0627 \u0643\u0627\u0646\u062a \u0636\u0631\u0648\u0631\u064a\u0629:<\/strong><\/p>\n<p>\u0627\u0633\u062a\u0626\u0635\u0627\u0644 \u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u0648\u0631\u0645 \u0623\u0648 \u0643\u0644\u0647 \u0628\u0639\u062f \u062a\u0646\u0648\u064a\u0645 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0648\u0627\u0644\u0642\u064a\u0627\u0645 \u0628\u0645\u0627 \u064a\u0633\u0645\u064a \u0645\u0642\u0637\u0639\u0627\u064b \u0645\u062b\u0644\u062c\u0627\u064b \u062c\u0645\u062f\u064a\u0627\u064b (Frozen Section) \u064a\u0639\u0646\u064a \u0641\u062d\u0635 \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0645\u0633\u062a\u0623\u0635\u0644 \u0645\u0646 \u0627\u0644\u0648\u0631\u0645. \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0623\u062b\u0646\u0627\u0621 \u064a\u0646\u062a\u0638\u0631 \u0627\u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u062c\u0631\u0627\u062d \u0639\u0627\u062f\u0629 \u0645\u0627 \u0628\u064a\u0646 \u0627\u0644\u0631\u0628\u0639 \u0633\u0627\u0639\u0629 \u0623\u0648 \u0627\u0644\u0633\u0627\u0639\u0629 \u062d\u0633\u0628 \u062a\u062c\u0647\u064a\u0632\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0634\u0641\u0649. \u0623\u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0645\u062e\u062a\u0628\u0631 \u0627\u0644\u0632\u0631\u0639 \u0628\u0639\u064a\u062f\u0627\u064b \u0639\u0646 \u0627\u0644\u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0630\u064a \u062a\u062a\u0645 \u0641\u064a\u0647 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0641\u0642\u062f \u062a\u0623\u062e\u0630 \u0648\u0642\u062a\u0627\u064b \u0623\u0637\u0648\u0644. \u0639\u0644\u0649 \u0623\u0633\u0627\u0633 \u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u0632\u0631\u0639 \u064a\u0642\u0631\u0631 \u0627\u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u062c\u0631\u0627\u062d \u0627\u0643\u0645\u0627\u0644 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0629. \u064a\u062c\u0628 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0627\u0644\u062c\u0631\u0627\u062d \u0642\u062f \u0646\u0627\u0642\u0634 \u0627\u0644\u0648\u0636\u0639 \u0645\u0639 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0642\u0628\u0644 \u0627\u0644\u062c\u0631\u0627\u062d\u0629\u060c \u0623\u0648 \u0645\u0639 \u0639\u0627\u0626\u0644\u062a\u0647\u0627 \u062e\u0644\u0627\u0644 \u0627\u0644\u062c\u0631\u0627\u062d\u0629 \u0641\u064a \u062d\u0627\u0644\u0627\u062a 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\u0645\u0627 \u0647\u064a \u0646\u062a\u0627\u0626\u062c \u0641\u062d\u0648\u0635\u0627\u062a \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a\u061f \u0645\u0627 \u0647\u064a \u0646\u062a\u064a\u062c\u0629 \u0641\u062d\u0635 \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u0631\u0648\u062c\u064a\u0646 \u0648\u0641\u062d\u0635 \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u062c\u0633\u062a\u0631\u0648\u0646 \u0648\u0645\u0627 \u0647\u064a \u0646\u0633\u0628\u062a\u0647\u0627\u061f \u0647\u0644 \u0647\u064a \u063a\u064a\u0631 \u0645\u0648\u062c\u0648\u062f\u0629 (\u0633\u0644\u0628\u064a\u0629) \u0623\u0648 \u0645\u0648\u062c\u0648\u062f\u0629 \u0628\u0646\u0633\u0628\u0629 \u0642\u0644\u064a\u0644\u0629 \u0623\u0648 \u0648\u0633\u0637\u064a\u0629 \u0623\u0648 \u0639\u0627\u0644\u064a\u0629\u061f<\/p>\n<p>9-\u00a0 \u0645\u0627 \u0647\u064a \u0646\u062a\u064a\u062c\u0629 \u0641\u062d\u0635 \u0628\u0631\u0648\u062a\u064a\u0646 \u0647\u064a\u0631 2 \u0646\u064a\u0648 CerbB2 (Her2\/Neu) \u0648\u0647\u0644 \u0647\u064a \u0632\u0627\u0626\u062f\u0629 \u0623\u0648 \u063a\u064a\u0631 \u0632\u0627\u0626\u062f\u0629\u061f \u0647\u0644 \u0647\u064a \u063a\u064a\u0631 \u0645\u0648\u062c\u0648\u062f\u0629 (0) \u0623\u0648 \u0645\u0648\u062c\u0648\u062f\u0629 \u0628\u0643\u0645\u064a\u0629 \u0642\u0644\u064a\u0644\u0629 (+1) \u0623\u0648 \u0628\u0643\u0645\u064a\u0629 \u0639\u0627\u0644\u064a\u0629: (Over-Expressed) (+++3+)\u060c \u0623\u0648 \u0648\u0633\u0637\u064a\u0629 (Equivocal ++2+:) \u062a\u062d\u062a\u0627\u062c \u0625\u0644\u0649 \u0641\u062d\u0635 \u062c\u064a\u0646\u064a \u0628\u0648\u0627\u0633\u0637\u0629 &#8220;\u0641\u064a\u0634 \u062a\u0633\u062a FISH Test \u0644\u062a\u062d\u062f\u064a\u062f \u0625\u0630\u0627 \u0645\u0627 \u0643\u0627\u0646 \u0639\u062f\u062f \u062c\u064a\u0646\u0627\u062a \u0647\u064a\u0631 2 \u0647\u0648 \u0628\u0627\u0644\u0641\u0639\u0644 \u0632\u0627\u0626\u062f\u0627 \u0648\u0645\u0636\u0627\u0639\u0641\u0627 \u0639\u0644\u0649 \u0627\u0644\u0643\u0631\u0645\u0648\u0632\u0648\u0645 17\u061f<\/p>\n<p>10-\u00a0\u00a0\u00a0\u00a0 \u0647\u0644 \u0648\u0635\u0644 \u0627\u0644\u0648\u0631\u0645 \u0625\u0644\u0649 \u0627\u0644\u0639\u0642\u062f \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629\u061f<\/p>\n<p>11-\u00a0\u00a0\u00a0\u00a0 \u0643\u0645 \u0639\u062f\u062f \u0627\u0644\u063a\u062f\u062f \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0645\u062a \u0625\u0632\u0627\u0644\u062a\u0647\u0627 \u0648\u0643\u0645 \u0647\u0648 \u0639\u062f\u062f \u0627\u0644\u0639\u0642\u062f \u0627\u0644\u062a\u064a \u0623\u0635\u064a\u0628\u062a \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629: \u0635\u0641\u0631 N0\u060c \u0645\u0646 1 &#8211; 3 (N1)\u060c \u0623\u0648 \u0645\u0646 4 \u0625\u0644\u0649 9 (N2)\u060c \u0623\u0648 10 \u0623\u0648 \u0623\u0643\u062b\u0631 (N3)\u061f<\/p>\n<p>12-\u00a0\u00a0\u00a0\u00a0 \u0647\u0644 \u0647\u0630\u0647 \u0627\u0644\u063a\u062f\u062f \u0645\u0635\u0627\u0628\u0629 \u0628\u062f\u0631\u062c\u0629 \u0627\u0646 \u063a\u0644\u0627\u0641 \u0627\u0644\u0639\u0642\u062f \u0623\u0635\u0628\u062d \u063a\u064a\u0631 \u0648\u0627\u0636\u062d\u0627\u064b \u0648\u0627\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0623\u0635\u0628\u062d\u062a \u062e\u0627\u0631\u062c \u0627\u0644\u063a\u0644\u0627\u0641 \u0648\u062d\u0648\u0644\u0647 \u0641\u064a \u0645\u062d\u064a\u0637\u0647 \u0627\u0644\u062f\u0647\u0646\u064a\u061f<\/p>\n<h2>\u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0644\u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0641 (Classification) \u0627\u0644\u062c\u062f\u064a\u062f \u0644\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a<\/h2>\n<p>\u064a\u0639\u062a\u0645\u062f \u0627\u0644\u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u062c\u062f\u064a\u062f \u0639\u0644\u0649 \u0627\u0644\u0641\u062d\u0635 \u0627\u0644\u0646\u0633\u064a\u062c\u064a \u0627\u0644\u0643\u0627\u0645\u0644 \u0645\u0639 \u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0644\u0645\u062a\u0644\u0642\u064a\u0627\u062a:<\/p>\n<p>1-\u00a0 \u062a\u062d\u062f\u064a\u062f \u0648\u062c\u0648\u062f \u062e\u0644\u0627\u064a\u0627 \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 (in-situ)<\/p>\n<p>2-\u00a0 \u062a\u062d\u062f\u064a\u062f \u0648\u062c\u0648\u062f \u062e\u0644\u0627\u064a\u0627 \u0633\u0631\u0637\u0627\u0646\u060c \u0625\u0630\u0627 \u0648\u062c\u062f\u062a: Carcinoma<\/p>\n<p>3-\u00a0 \u062a\u062d\u062f\u064a\u062f \u0646\u0648\u0639 \u0627\u0644\u0633\u0631\u0637\u0627\u0646: \u0627\u0644\u0646\u0648\u0639\u064a\u0646 \u0627\u0644\u0623\u0643\u062b\u0631 \u062d\u062f\u0648\u062b\u0627\u064b \u0647\u0645 \u0633\u0631\u0637\u0627\u0646 \u0642\u0646\u0648\u0627\u062a \u0627\u0644\u062d\u0644\u064a\u0628 Infiltrating Ductal Carcinoma \u0623\u0648 \u0633\u0631\u0637\u0627\u0646 \u063a\u062f\u062f \u0627\u0644\u062d\u0644\u064a\u0628 Infiltrating Lobular Carcinoma.<\/p>\n<p>4-\u00a0 \u062a\u062d\u062f\u064a\u062f \u062f\u0631\u062c\u0629 \u0648\u0633\u0631\u0639\u0629 \u0646\u0645\u0648 \u0627\u0644\u062e\u0644\u0627\u064a\u0627: \u0645\u0646 \u0642\u0644\u064a\u0644\u0629 &#8211; \u0628\u0637\u064a\u0626\u0629 (Grade 1) \u0623\u0648 \u0639\u0627\u0644\u064a\u0629 &#8211; \u0633\u0631\u064a\u0639\u0629 (Grade 3)\u060c \u0623\u0648 \u062f\u0631\u062c\u0629 \u0645\u062a\u0648\u0633\u0637\u0629 (Grade 2).<\/p>\n<p>5-\u00a0 \u064a\u0642\u0648\u0645 \u0637\u0628\u064a\u0628 \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u0628\u0625\u062c\u0631\u0627\u0621 \u062a\u0644\u0648\u064a\u0646\u0627\u062a \u0645\u0646\u0627\u0639\u064a\u0629 \u0646\u0633\u064a\u062c\u064a\u0629 \u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0646\u0633\u0645\u064a\u0647\u0627 Immuno Histo Chemical Stains\/IHC)) \u0644\u0645\u0639\u0631\u0641\u0629 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0648\u0631\u0645 \u064a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0646\u0633\u0627\u0626\u064a\u0629 \u0627\u0633\u062a\u0631\u0648\u062c\u064a\u0646 Estrogen Receptors \u0648\u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0628\u0631\u0648\u062c\u064a\u0633\u062a\u064a\u0631\u0648\u0646 Progesterone Receptors \u062f\u0627\u062e\u0644 \u0646\u0648\u0627\u0629 \u0627\u0644\u062e\u0644\u064a\u0629.<\/p>\n<p>6-\u00a0 \u0627\u0630\u0627 \u0643\u0627\u0646\u062a \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a\u062a\u0645 \u062a\u062d\u062f\u064a\u062f \u063a\u0632\u0627\u0631\u062a\u0647\u0627 (Intensity) \u0648\u0643\u0630\u0644\u0643 \u0646\u0633\u0628\u0629 \u0639\u062f\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u064a \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u064a\u0647\u0627 (Percentage of cells positive).<\/p>\n<p>7-\u00a0 \u064a\u062a\u0645 \u062a\u062d\u062f\u064a\u062f \u0648\u062c\u0648\u062f \u0648\u0646\u0633\u0628\u0629 \u0648\u062c\u0648\u062f \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0647\u064a\u06312\/\u0646\u064a\u0648\/Human Epithelial Receptors HER2\/Neu \u0639\u0644\u0649 \u0633\u0637\u062d \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629: 0\u060c +\u060c ++\u060c \u0623\u0648 +++\u060c \u0648\u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0632\u0627\u0626\u062f\u0629 (\u0623\u0646\u0638\u0631 \u0644\u0627\u062d\u0642\u0627) \u0641\u0647\u064a \u0642\u062f \u062a\u0639\u0646\u064a \u0623\u0646 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0642\u062f \u064a\u062a\u0645\u062a\u0639 \u0628\u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0646\u0645\u0648 \u0632\u0627\u0626\u062f.<\/p>\n<p>8-\u00a0 \u0644\u0642\u062f \u0623\u0635\u0628\u062d\u0646\u0627 \u0646\u0639\u062a\u0628\u0631 \u0623\u0646 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0647\u0646\u0627\u0643 \u0623\u0643\u062b\u0631 \u0645\u0646 1% \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0627\u0633\u062a\u0631\u0648\u062c\u064a\u0646\/\u0628\u0631\u0648\u062c\u0633\u062a\u064a\u0631\u0648\u0646 \u0641\u0627\u0646 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0642\u062f \u062a\u0633\u062a\u0641\u064a\u062f \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a.<\/p>\n<p>9-\u00a0 \u0646\u062a\u064a\u062c\u0629 \u0647\u064a\u06312 \u062a\u0639\u062a\u0628\u0631 \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0632\u0627\u0626\u062f\u0629 \u0639\u0646\u062f\u0645\u0627 \u062a\u0643\u0648\u0646 \u0646\u0633\u0628\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0627\u0644\u062a\u0644\u0648\u064a\u0646 \u0627\u0644\u0643\u0627\u0645\u0644 \u0641\u0648\u0642 30% \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 (+++)\u060c \u0623\u0648 \u0623\u0646 \u0627\u0644\u0646\u0633\u0628\u0629 \u0623\u0642\u0644 (++) \u0648\u064a\u0643\u0648\u0646 \u0641\u062d\u0635 \u062c\u064a\u0646 \u0627\u0644\u0647\u064a\u06312 HER2 gene \u0627\u0644\u0630\u064a \u0646\u0633\u0645\u064a\u0647 FISH test \u0646\u0633\u0628\u062a\u0647 \u0645\u0636\u0627\u0639\u0641\u0629 (\u0628\u0648\u0632\u064a\u062a\u064a\u0641) \u0639\u0646\u062f\u0626\u0630 \u0642\u062f \u062a\u0633\u062a\u0641\u064a\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0645\u0646 \u0645\u0636\u0627\u062f\u0627\u062a \u0647\u064a\u06312 \u0645\u062b\u0644 \u062a\u0631\u0627\u0633\u062a\u0648\u0632\u0648\u0645\u0627\u0628 \u0623\u0648 \u0644\u0627\u0628\u0627\u062a\u064a\u0646\u064a\u0628 \u0623\u0648 \u0628\u064a\u0631\u062a\u0648\u0632\u0648\u0645\u0627\u0628 \u0623\u0648 \u062a\u064a \u062f\u064a \u0623\u0645 \u0648\u0627\u0646 \u0648\u0645\u0627 \u0642\u062f \u064a\u062a\u0645 \u0627\u0643\u062a\u0634\u0627\u0641\u0647 \u0644\u0627\u062d\u0642\u0627\u064b.<\/p>\n<p>10-\u00a0\u00a0\u00a0\u00a0 \u0641\u062d\u0635 \u0628\u0631\u0648\u062a\u064a\u0646 \u0643\u064a \u0623\u064a 67 (Ki67) \u0645\u0624\u0634\u0631 \u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u0633\u0631\u064a\u0639 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0632\u0627\u0626\u062f\u0627\u064b \u0641\u064a \u0639\u062f\u062f \u0643\u0628\u064a\u0631 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627. \u0646\u062a\u064a\u062c\u0629 \u0647\u0630\u0627 \u0627\u0644\u0641\u062d\u0635 \u0645\u0627 \u0632\u0627\u0644\u062a \u063a\u064a\u0631 \u0645\u062f\u0648\u0632\u0646\u0629 \u0628\u064a\u0646 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0648\u0645\u0627 \u0632\u0627\u0644 \u0627\u0633\u062a\u0639\u0645\u0627\u0644\u0647 \u0645\u062d\u062f\u0648\u062f \u0625\u0644\u0627 \u0641\u064a \u0628\u0639\u0636 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0648\u0627\u0644\u0645\u0633\u062a\u0634\u0641\u064a\u0627\u062a \u0630\u0627\u062a \u0627\u0644\u062e\u0628\u0631\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0628\u0647.<\/p>\n<h2>\u0627\u0644\u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u062d\u062f\u064a\u062b \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u0644\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a<\/h2>\n<p>\u0628\u0646\u0627\u0621 \u0639\u0644\u0649 \u0623\u0639\u0644\u0627\u0647:<\/p>\n<p>\u064a\u062a\u0645 \u062a\u0642\u0633\u064a\u0645 \u0648\u062a\u0635\u0646\u064a\u0641 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0625\u0644\u0649 \u0627\u0644\u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u062a\u0627\u0644\u064a\u0629:<\/p>\n<p>1- \u0644\u0648\u0645\u064a\u0646\u0627\u0644 \u0623: Luminal A: ER+, PR+, HER2-, Grade 1<\/p>\n<p>2- \u0644\u0648\u0645\u064a\u0646\u0627\u0644 \u0628: Luminal B: ER+ ,PR+ (&lt;20%) or -, HER2-, Grade 3, Ki67 high (if reliable)<\/p>\n<p>3- \u0644\u0648\u0645\u064a\u0646\u0627\u0644 \u0628: Luminal B: ER+, PR+, HER2+<\/p>\n<p>4- \u0647\u064a\u0631 2 \u0632\u0627\u0626\u062f: HER2-overexpressive<\/p>\n<p>5- \u062b\u0644\u0627\u062b\u064a \u0627\u0644\u0633\u0644\u0628\u064a\u0629 \u0648- \u0623\u0648 \u0628\u0627\u0632\u0627\u0644: Triple Negative Breast Cancer (TNBC) , and\/or Basal-Like Breast Cancer (BLBC)<\/p>\n<h2>\u0641\u062d\u0648\u0635\u0627\u062a \u0625\u0636\u0627\u0641\u064a\u0629 \u062c\u064a\u0646\u064a\u0629 \u062c\u0632\u064a\u0626\u064a\u0629 \u062d\u062f\u064a\u062b\u0629 \u0645\u0633\u0627\u0639\u062f\u0629 \u0644\u0642\u0631\u0627\u0631\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0623\u0648 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a \u0641\u0642\u0637 \u0628\u062f\u0648\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a<\/h2>\n<p>\u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0646\u0643\u0648\u062a\u0627\u064a\u0628 &#8211; \u062f\u064a- \u0627\u0643\u0633: Oncotype Dx<\/p>\n<p>\u062a\u0645\u062a \u062f\u0631\u0627\u0633\u0627\u062a \u062d\u062f\u064a\u062b\u0629 \u0639\u0644\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 21 \u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0646\u0645\u0648 (proliferation genes) \u0648\u062c\u064a\u0646\u0627\u062a \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0647\u0631\u0645\u0648\u0646\u064a\u0629 \u0648\u062a\u062d\u062f\u064a\u062f \u0623\u062b\u0631\u0647\u0627 \u0639\u0644\u0649 \u0646\u0645\u0648 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0648\u0646\u0633\u0628\u0629 \u0631\u062c\u0648\u0639 \u0627\u0644\u0645\u0631\u0636 \u0628\u0639\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0648\u0633\u0645\u064a\u062a \u0641\u062d\u0635 Recurrence Score-21 (\u0627\u0646\u0643\u0648\u062a\u0627\u064a\u0628 \u062f\u064a \u0627\u0643\u0633: Oncotype Dx).<\/p>\n<p>\u0646\u0633\u062a\u0637\u064a\u0639 \u0628\u0648\u0627\u0633\u0637\u0629 \u0627\u0646\u0643\u0648\u062a\u0627\u064a\u0628 \u062f\u064a \u0627\u0643\u0633 \u0627\u0644\u062a\u0643\u0647\u0646 \u0628\u0646\u0633\u0628\u0629 \u062e\u0637\u0648\u0631\u0629 \u0639\u0648\u062f\u0629 \u0627\u0644\u0645\u0631\u0636 \u062d\u0633\u0628 \u0627\u062d\u062a\u0633\u0627\u0628 \u0646\u0633\u0628\u0629 score:. \u0641\u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0646\u0642\u0627\u0637 \u0639\u0627\u0644\u064a\u0629 (High Score: Abore 31) \u0641\u062a\u0643\u0648\u0646 \u0646\u0633\u0628\u0629 \u0627\u062d\u062a\u0645\u0627\u0644 \u0639\u0648\u062f\u0629 \u0627\u0644\u0645\u0631\u0636 \u0623\u0639\u0644\u0649 \u0648\u0627\u0644\u0627\u0633\u062a\u0641\u0627\u062f\u0629 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u0627\u0626\u064a \u0645\u0639\u0642\u0648\u0644\u0629 \u0648\u0645\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0627\u0633\u062a\u0641\u0627\u062f\u0629 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a \u0648\u064a\u0633\u062a\u062d\u0633\u0646 \u0627\u0633\u062a\u0639\u0645\u0627\u0644\u0647. \u0623\u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0646\u0642\u0627\u0637 \u0642\u0644\u064a\u0644\u0629 \u0641\u064a\u0643\u0648\u0646 \u0627\u062d\u062a\u0645\u0627\u0644 \u0639\u0648\u062f\u0629 \u0627\u0644\u0645\u0631\u0636 \u0642\u0644\u064a\u0644\u0629 \u062c\u062f\u0627\u064b \u0648\u064a\u0639\u0646\u064a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0644\u0627 \u064a\u0632\u064a\u062f \u0623\u0641\u0627\u062f\u0629 \u0648\u064a\u0645\u0643\u0646 \u0627\u0644\u0627\u0643\u062a\u0641\u0627\u0621 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a \u0627\u0644\u0645\u0636\u0627\u062f. \u0627\u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0627\u0644\u0646\u0633\u0628\u0629 \u0645\u062a\u0648\u0633\u0637\u0629 (Intermediate Score between 18-31) \u0641\u064a\u0628\u0642\u0649 \u0644\u0644\u0637\u0628\u064a\u0628 \u0627\u0646 \u064a\u062f\u0631\u0633 \u0633\u0627\u0626\u0631 \u0627\u0644\u0645\u0639\u0637\u064a\u0627\u062a \u0644\u064a\u0642\u0631\u0631 \u0645\u0627 \u0643\u0627\u0646 \u064a\u062c\u0628 \u0625\u0639\u0637\u0627\u0621 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0643\u064a\u0645\u0627\u0626\u064a\u0629 \u0623\u0648 \u0627\u0644\u0627\u0643\u062a\u0641\u0627\u0621 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u060c \u0623\u0648 \u0627\u062f\u062e\u0627\u0644 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0641\u064a \u062a\u062c\u0627\u0631\u0628 \u0633\u0631\u064a\u0631\u064a\u0629.<\/p>\n<p>\u0648\u0647\u0646\u0627 \u0646\u0634\u064a\u0631 \u0625\u0644\u0649 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0643\u062a\u0645\u0644\u062a \u0641\u064a \u0623\u0645\u064a\u0631\u0643\u0627 (TAILORx) \u0646\u062d\u0646 \u0628\u0627\u0646\u062a\u0638\u0627\u0631 \u0646\u062a\u0627\u0626\u062c\u0647\u0627. \u064a\u0645\u0643\u0646 \u0637\u0644\u0628 \u0647\u0630\u0627 \u0627\u0644\u0641\u062d\u0635 \u0639\u0646\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0630\u0627\u062a \u0627\u0644\u0648\u0631\u0645 \u0627\u0644\u0635\u063a\u064a\u0631 \u0648\u0639\u062f\u062f \u0627\u0644\u0639\u0642\u062f \u0627\u0644\u0644\u064a\u0645\u0641\u0627\u0648\u064a\u0629 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0645\u0646 \u0635\u0641\u0631 \u0625\u0644\u0649 \u062b\u0644\u0627\u062b\u0629 \u0648\u064a\u0643\u0648\u0646 \u0627\u0644\u0648\u0631\u0645 \u064a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0627\u0633\u062a\u0631\u0648\u062c\u064a\u0646 \u0648\u0628\u0631\u0648\u062c\u064a\u0633\u062a\u064a\u0631\u0648\u0646 (\u0628\u0648\u0632\u062a\u064a\u0641) \u0648\u0644\u0627 \u064a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0645\u062a\u0644\u0642\u064a\u0627\u062a \u0647\u064a\u0631 2 (\u0646\u064a\u063a\u0627\u062a\u064a\u0641). \u0639\u0646\u062f\u0645\u0627 \u064a\u0631\u064a\u062f \u0627\u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u062a\u0623\u0643\u062f \u0645\u0646 \u0623\u0646 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u064a\u0645\u0643\u0646 \u0645\u0639\u0627\u0644\u062c\u062a\u0647\u0627 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a \u0641\u0642\u0637 \u0648\u0627\u0644\u0627\u0633\u062a\u063a\u0646\u0627\u0621 \u0639\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a. \u0648\u0646\u0634\u064a\u0631 \u0623\u0646\u0647 \u0628\u0627\u0644\u0625\u0645\u0643\u0627\u0646 \u0625\u062c\u0631\u0627\u0621 \u0641\u062d\u0635 \u0627\u0646\u0643\u0648\u062a\u0627\u064a\u0628 \u062f\u064a \u0627\u0643\u0633 \u0639\u0644\u0649 \u0646\u0633\u064a\u062c \u0628\u0644\u0648\u0643 \u0627\u0644\u0634\u0645\u0639\u060c \u0628\u0639\u062f \u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u062c\u0631\u0627\u062d\u0629 \u0623\u0648 \u0627\u0644\u062e\u0632\u0639\u0629.<\/p>\n<h2>\u0641\u062d\u0648\u0635\u0627\u062a Mammaprint<\/h2>\n<p>\u0647\u0646\u0627\u0643 \u0623\u064a\u0636\u0627\u064b \u0645\u062c\u0645\u0648\u0639\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0633\u0628\u0639\u064a\u0646 \u062c\u064a\u0646 (70Gene) \u062a\u0645 \u0627\u0643\u062a\u0634\u0627\u0641\u0647\u0627 \u0648\u062a\u062d\u062f\u064a\u062f\u0647\u0627 \u0641\u064a \u0627\u0645\u0633\u062a\u0631\u062f\u0627\u0645 \u0648\u062a\u0633\u0645\u0649 (Amesterdam 70 gene Signature Score \u064a\u062a\u0645 \u0645\u0646 \u062e\u0644\u0627\u0644\u0647\u0627 \u0641\u062d\u0635 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u062c\u064a\u0646\u0627\u062a gene microarray \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0628\u0627\u062b\u0648\u0644\u0648\u062c\u064a\u0629. \u0648\u062d\u0633\u0628 \u062a\u062c\u0645\u0639 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u064a\u062a\u0645 \u062a\u062d\u062f\u064a\u062f \u0645\u0627 \u064a\u0633\u0645\u0649 \u0628\u0623\u0648\u0631\u0627\u0645 \u0630\u0627\u062a \u0627\u062d\u062a\u0645\u0627\u0644 \u0631\u0648\u062c\u0639\u0629 \u0642\u0644\u064a\u0644\u0629 \u0623\u064a &#8220;\u0627\u0645\u0636\u0627\u0621 \u062c\u064a\u062f&#8221;\u060c \u0648\u064a\u0645\u0643\u0646 \u0625\u0639\u0637\u0627\u0621 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 \u0639\u0644\u0627\u062c\u0627\u064b \u0647\u0631\u0645\u0648\u0646\u064a\u0627 \u0645\u0636\u0627\u062f\u0627 \u0648\u0628\u062f\u0648\u0646 \u0639\u0644\u0627\u062c \u0643\u064a\u0645\u0627\u0626\u064a. \u0627\u0645\u0627 \u0625\u0630\u0627 \u0623\u0639\u0637\u062a \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0645\u0627 \u0646\u0633\u0645\u064a\u0647 \u0627\u0645\u0636\u0627\u0621 \u0633\u064a\u0621 (Bad Signature) \u0641\u062a\u0643\u0648\u0646 \u062e\u0637\u0648\u0631\u0629 \u0631\u0648\u062c\u0639\u0629 \u0627\u0644\u0645\u0631\u0636 \u0639\u0627\u0644\u064a\u0629 \u0646\u0633\u0628\u064a\u0627\u064b \u0648\u064a\u062a\u0648\u062c\u0628 \u0625\u0639\u0637\u0627\u0621 \u0627\u0644\u0645\u0631\u064a\u0636\u0629 \u0639\u0644\u0627\u062c\u0627\u064b \u0643\u064a\u0645\u0627\u0626\u064a\u0627\u064b. \u0627\u0645\u0627 \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0648\u0633\u0637\u064a\u0629 \u0641\u0645\u0627 \u0632\u0644\u0646\u0627 \u0628\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u062f\u0631\u0627\u0633\u0627\u062a \u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u064a\u0627\u062f\u064a\u0629 \u0643\u0644\u064a\u0646\u064a\u0643\u064a\u0647 \u0644\u0625\u0639\u0637\u0627\u0621 \u062c\u0648\u0627\u0628 \u0646\u0647\u0627\u0626\u064a \u0648\u0623\u0647\u0645\u0647\u0627 \u0641\u064a \u0623\u0648\u0631\u0648\u0628\u0627 \u062f\u0631\u0627\u0633\u0629 Mindact \u0627\u0644\u062a\u064a \u062a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 Amsterdam 70-Gene Signature. \u0623\u0646\u0646\u0627 \u0646\u0623\u0645\u0644 \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 (\u0645\u0639 \u062f\u0631\u0627\u0633\u0629 TAILORx) \u0623\u0646 \u062a\u0638\u0647\u0631 \u0644\u0646\u0627 \u0628\u0634\u0643\u0644 \u0627\u0648\u0636\u062d \u0645\u0646 \u0647\u0646 \u0627\u0644\u0633\u064a\u062f\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u064a\u0645\u0643\u0646 \u0639\u062f\u0645 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\u0645\u062c\u0645\u0648\u0639\u0629 \u0641\u062d\u0648\u0635\u0627\u062a \u062c\u064a\u0646\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0644\u0640 12 \u062c\u064a\u0646 \u062a\u0639\u0637\u064a \u0631\u0642\u0645 score \u0625\u0630\u0627 \u0643\u0627\u0646 \u0639\u0627\u0644\u064a\u0627\u064b \u062a\u0643\u0648\u0646 \u0646\u0633\u0628\u0629 \u062e\u0637\u0648\u0631\u0629 \u0639\u0648\u062f\u0629 \u0627\u0644\u0645\u0631\u0636 \u0632\u0627\u0626\u062f\u0629.<\/p>\n<h2>\u0641\u062d\u0648\u0635\u0627\u062a PAM50<\/h2>\n<p>\u0647\u0630\u0647 \u0623\u064a\u0636\u0627\u064b \u0637\u0631\u064a\u0642\u0629 \u0644\u062a\u062d\u062f\u064a\u062f \u0646\u0633\u0628\u0629 \u062e\u0637\u0648\u0631\u0629 \u0639\u0648\u062f\u0629 \u0627\u0644\u0645\u0631\u0636 \u064a\u0645\u0643\u0646 \u0627\u0639\u062a\u0645\u0627\u062f\u0647\u0627 \u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0627\u0644\u0632\u0631\u0639 \u0628\u062f\u0644 \u0625\u0631\u0633\u0627\u0644 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\u0647\u0630\u0647 \u0627\u0644\u0639\u0642\u062f \u0627\u0645\u0627 \u0641\u064a \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0623\u0639\u0644\u0649 \u0627\u0644\u0642\u0631\u064a\u0628 \u0645\u0646 \u0627\u0644\u0625\u0628\u0637\u060c \u0623\u0648 \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u062b\u0644\u0627\u062b \u062a\u062d\u062a \u0627\u0644\u0625\u0628\u0637 (Axillary Lymph Nodes Level I, Level II, and Level III)\u060c \u0623\u0648 \u0641\u064a \u062f\u0627\u062e\u0644 \u0627\u0644\u0642\u0641\u0635 \u0627\u0644\u0635\u062f\u0631\u064a \u0648\u062a\u0633\u0645\u0649 \u0639\u0642\u062f \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629 (Internal Mammary Chain)\u060c \u0623\u0648 \u0641\u0648\u0642 \u0639\u0638\u0645\u0629 \u0627\u0644\u062a\u0631\u0642\u0648\u0629 \u0641\u064a \u0623\u0633\u0641\u0644 \u0627\u0644\u0631\u0642\u0628\u0629 (Supraclavicular Lymph nodes).<\/p>\n<h2>\u0643\u064a\u0641 \u064a\u0645\u0643\u0646 \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0627\u0646\u062a\u0634\u0627\u0631 \u0641\u064a \u0639\u0642\u062f \u0627\u0644\u0625\u0628\u0637<\/h2>\n<p>\u064a\u0639\u062a\u0628\u0631 \u0641\u062d\u0635 \u0648\u0627\u0633\u062a\u0626\u0635\u0627\u0644 \u0639\u0642\u062f \u062a\u062d\u062a \u0627\u0644\u0625\u0628\u0637 \u062c\u0632\u0621\u0627\u064b \u0645\u0646 \u0639\u0644\u0627\u062c \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0646\u0647 \u064a\u0639\u0637\u064a \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u0636\u0631\u0648\u0631\u064a\u0629 \u062d\u0648\u0644 \u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0645\u0631\u0636 \u0628\u063a\u0631\u0636 \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062a\u0627\u0644\u064a\u0629 \u0628\u0639\u062f \u0627\u0644\u062c\u0631\u0627\u062d\u0629.<\/p>\n<p>\u064a\u062a\u0645 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