السلام عليكم جميعا ..
عندي السبت بريزنتيشن عن ال acute inflammation
وعندي الموضوع كامل بس حابة احد يعلمني طريقة الشرح بالعربي ..!!
واتمنى الرد قبل يوم السبت . ولكم مني خالص الدعاء وجزاكم الله خيراً
هذا الموضوع كامل ::
Acute inflammation is an early defense mechanism to contain an infection , prevent it’s spread from the initial focus, and signal subsequent specific immune responses . the three major events in acute inflammation are : (1) expansion of capillaries to increase blood flow (causing redness or rash and releasing heat) (2) increase in permeability of the microvasculature structure to allow escape of fluid, plasma proteins, and leukocytes from the circulation (swelling or edema ) and (3) recruitment of neutrophils and their accumulation and response to infection at the site of injury .
Inflammatory responses are beneficial but are associated with pain , redness , heat and swelling and can also cause tissue damage . tissue damage is caused to some extent by complement and macrophages but mostly by neutrophils . dead neutrophils are a major component of pus . kinins and clotting factors induced by tissue damage ( e.g. factor XXII [Hageman factor ] , bradykinin, fibrinopeptides ) are also involved in inflammation . these factors increase vascular permeability and are chemotactic for leukocytes . products of arachidonic acid metabolism also affect inflammation . cyclooxygenase-2 (COX-2) and 5-lipooxygenese convert arachidonic acid to prostaglandins and leukorienes, respectively , which can mediate essentially every aspect of acute inflammation . the course of inflammation can be followed by rapid increase in acute phase proteins, especially C-reactive protein (which can increase a thousand fold within 24 to 28 hours ) and serum amyloid A
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